This course is a comprehensive course intended for science majors. Topics covered include the basic structure and reactions of biological compounds (carbohydrates, lipids, proteins, enzymes, and nucleic acids), the digestion and absorption of nutrients, bioenergetic principles, and catabolic and anabolic metabolism of major biochemicals in the human body. The laboratory exercises include classic techniques in isolation, purification and assay of proteins, enzymes (and kinetics), carbohydrates, lipids, and nucleic acids as well as polypeptide and polynucleotide sequencing and synthesis.